diff --git a/i2c-tools.spec b/i2c-tools.spec
index d2ff75e..58a3d8a 100644
--- a/i2c-tools.spec
+++ b/i2c-tools.spec
@@ -4,9 +4,15 @@
 # This file and all modifications and additions to the pristine
 # package are under the same license as the package itself.
 
+%if 0%{?rhel} > 7 || 0%{?fedora} > 28
+%bcond_with python2
+%else
+%bcond_without python2
+%endif
+
 Name:           i2c-tools
 Version:        4.0
-Release:        4%{?dist}
+Release:        5%{?dist}
 Summary:        A heterogeneous set of I2C tools for Linux
 License:        GPLv2+
 URL:            https://i2c.wiki.kernel.org/index.php/I2C_Tools
@@ -21,7 +27,10 @@ Patch2:         0003-py-smbus-Fix-FSF-address-in-smbusmodule.c.patch
 # for /etc/udev/makedev.d resp /etc/modprobe.d ownership
 Requires:       udev module-init-tools
 BuildRequires:  perl-generators
-BuildRequires:  python2-devel python3-devel
+%if %{with python2}
+BuildRequires:  python2-devel
+%endif
+BuildRequires:  python3-devel
 BuildRequires:  gcc
 ExcludeArch:    s390 s390x
 
@@ -42,6 +51,7 @@ eeproms in your system is very dangerous and is likely to render your system
 unusable. Do not install, let alone use this, unless you really, _really_ know
 what you are doing.
 
+%if %{with python2}
 %package -n python2-i2c-tools
 %{?python_provide:%python_provide python2-i2c-tools}
 # Remove before F30
@@ -52,9 +62,16 @@ Summary:        Python 2 bindings for Linux SMBus access through i2c-dev
 
 %description -n python2-i2c-tools
 Python 2 bindings for Linux SMBus access through i2c-dev
+%endif
 
 %package -n python3-i2c-tools
 %{?python_provide:%python_provide python3-i2c-tools}
+%if %{without python2}
+# Remove before F30
+Obsoletes: %{name}-python < 4.0-4
+# Remove before F31
+Obsoletes: python2-i2c-tools < 4.0-5
+%endif
 Summary:        Python 3 bindings for Linux SMBus access through i2c-dev
 
 %description -n python3-i2c-tools
@@ -96,8 +113,10 @@ pushd eepromer
 make CFLAGS="$RPM_OPT_FLAGS -I../include" LDFLAGS="$RPM_LD_FLAGS"
 popd
 pushd py-smbus
+%if %{with python2}
 CFLAGS="$RPM_OPT_FLAGS -I../include" LDFLAGS="$RPM_LD_FLAGS" \
   %{__python2} setup.py build -b build-py2
+%endif
 CFLAGS="$RPM_OPT_FLAGS -I../include" LDFLAGS="$RPM_LD_FLAGS" \
   %{__python3} setup.py build -b build-py3
 popd
@@ -111,7 +130,9 @@ install -m 755 eepromer/{eepromer,eeprom} \
 install -m 644 eepromer/{eepromer,eeprom}.8 \
   $RPM_BUILD_ROOT%{_mandir}/man8
 pushd py-smbus
+%if %{with python2}
 %{__python2} setup.py build -b build-py2 install --skip-build --root=$RPM_BUILD_ROOT
+%endif
 %{__python3} setup.py build -b build-py3 install --skip-build --root=$RPM_BUILD_ROOT
 popd
 # cleanup
@@ -163,9 +184,11 @@ exit 0
 %{_sbindir}/eepro*
 %{_mandir}/man8/eepro*.8.gz
 
+%if %{with python2}
 %files -n python2-i2c-tools
 %doc py-smbus/README
 %{python2_sitearch}/*
+%endif
 
 %files -n python3-i2c-tools
 %doc py-smbus/README
@@ -189,6 +212,9 @@ exit 0
 
 
 %changelog
+* Thu Mar 22 2018 Ondřej Lysoněk <olysonek@redhat.com> - 4.0-5
+- Don't build Python 2 subpackage on EL > 7 and Fedora > 28
+
 * Mon Feb 19 2018 Ondřej Lysoněk <olysonek@redhat.com> - 4.0-4
 - Add gcc to BuildRequires