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diff -up EMBOSS-6.4.0/configure.in.system-zlib EMBOSS-6.4.0/configure.in
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--- EMBOSS-6.4.0/configure.in.system-zlib	2011-11-23 17:07:55.000000000 +0100
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+++ EMBOSS-6.4.0/configure.in	2011-11-23 17:08:36.848586027 +0100
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@@ -644,6 +644,7 @@ if test "${enable_systemlibs}" = "yes" ;
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   have_systemlibs=yes
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   AC_CHECK_LIB(pcre, pcre_compile)
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   AC_CHECK_LIB(expat, XML_ParserCreate)
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+  AC_CHECK_LIB(z, compress)
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 fi
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 AM_CONDITIONAL([ESYSTEMLIBS], [test "$have_systemlibs" = "yes"])
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 AC_SUBST([ESYSTEMLIBS])
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@@ -808,7 +809,6 @@ AC_CONFIG_FILES([Makefile
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                  ajax/core/Makefile
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                  ajax/ensembl/Makefile
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                  ajax/graphics/Makefile
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-                 ajax/zlib/Makefile
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                  doc/Makefile
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                  doc/manuals/Makefile
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                  doc/programs/Makefile
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diff -up EMBOSS-6.4.0/configure.system-zlib EMBOSS-6.4.0/configure