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diff -up EMBOSS-6.4.0/configure.in.system-expat EMBOSS-6.4.0/configure.in
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--- EMBOSS-6.4.0/configure.in.system-expat	2011-11-23 17:06:08.000000000 +0100
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+++ EMBOSS-6.4.0/configure.in	2011-11-23 17:07:00.615161077 +0100
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@@ -643,6 +643,7 @@ AC_ARG_ENABLE([systemlibs],
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 if test "${enable_systemlibs}" = "yes" ; then
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   have_systemlibs=yes
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   AC_CHECK_LIB(pcre, pcre_compile)
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+  AC_CHECK_LIB(expat, XML_ParserCreate)
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 fi
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 AM_CONDITIONAL([ESYSTEMLIBS], [test "$have_systemlibs" = "yes"])
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 AC_SUBST([ESYSTEMLIBS])
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@@ -806,7 +807,6 @@ AC_CONFIG_FILES([Makefile
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                  ajax/ajaxdb/Makefile
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                  ajax/core/Makefile
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                  ajax/ensembl/Makefile
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-                 ajax/expat/Makefile
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                  ajax/graphics/Makefile
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                  ajax/zlib/Makefile
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                  doc/Makefile
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diff -up EMBOSS-6.4.0/configure.system-expat EMBOSS-6.4.0/configure